Completed Studies

Completed Studies

Now in TPIDA, we have about 20 core members, including infectious diseases specialists, virologists, molecular biologists, and more than 30 technicians and assistants working together.

From 2010, TPIDA has conducted a nation-wide survey of pediatric pneumonia. We enrolled patients diagnosed as community acquired pneumonia in all study sites of our team. Their clinical data were recorded and specimens including serum, nasopharyngeal aspirates and cultured bacteria were collected. We have enrolled almost 1000 patients who were diagnosed as community acquired pneumonia in 3 years.

In 2011, we also conducted a survey of antimicrobial usage and nasal methicillin-resistant Staphylococcus aureus carriage in pediatric and neonatal intensive care units (ICUs).

In this project, one-time point prevalence survey for antibiotic usage in the study subjects were performed on two designated dates. On the designated dates, each patient stayed in NICU and PICU of the participating hospitals of TPIDA was recruited, and the data of demographics, underlying diseases as well as the usage of antibiotics were collected.

About 250 nasal swabbed samples were collected. We found that 12.6-13.6% of paticents admitted to the ICUs in the TPIDA hospitals around the island were colonized with S. aureus. Among which, MRSA colonization contributed to 30% of all Staphylococcus aureus.

Before this study, the only data for MRSA carriage rate in Taiwanese pediatric/neonatal ICU patients was from a single-center study. During 2003-04, 41% infants admitted to the NICUs were colonized with MRSA during their stay in NICUs of this medical center.

The results of this collaborative study highlight the great importance of the development of an island-wide clinical research network. Although we are living in a small island, a single-center study cannot explain the full picture of reality. In this successful TPIDA study, we could identify that MRSA colonization in neonatal ICU patients is a single center matter rather than an island-wide issue in a short time. Furthermore, through this project, we also realized the current status of antimicrobial use in NICU and PICU population in Taiwan.