Current Activities

Current IIT or Clinical Studies Under TLC

  1. An open-label, multi-center, randomized study comparing entecavir plus Pegasys vs. entecavir alone in the treatment of hepatitis B antigen-positive chronic hepatitis B
  2. Long-term follow-up of B+C cohort s/p treatment with Pegasys and ribavirin
  3. Prevention of HCC recurrent by entecavir therapy in HCC patients receiving curative RFA
  4. Total anti-HBc titer as a marker for host immune activity against HBV: A predictor for treatment response?
  5. An extension, observational study (1) to evaluate the long term effects of peginterferon alfa-2a plus ribavirin for patients with chronic hepatitis C/chronic B co-infection and chronic hepatitis C mono-infection, and (2) to evaluate the host and viral factors associated with the treatment effects
  6. Alcoholic and nonalcoholic fatty liver disease in Taiwan

New proposals to be covered by TLC

  1. Peg-IFN alfa-2a plus entecavir for the treatment of HBeAg-negative chronic hepatitis B
  2. Unique genetic traits associated with hyper-response to Pegasys treatment for CHB 
  3. Long-term follow-up of CHB patients at risk of developing HCC (With/Without treatment)